APPROPRIATE FLUOROBENZAMIDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE OR SENILE DEMENTIA.

摘要

Compounds of the general formula ** (See formula) ** wherein R1 is hydrogen, (C1-C6) -alkyl or hydroxy- (C1-C6) -alkyl; R2 is (C1-C6) -alkyl, -CO-NR 8 R 9, - (CH2) n-NR8 R9, - (CH2) P-OR 8, or - (CH2) n-CN; R3 is selected from hydrogen, halogen, halogen- (C1-C6) -alkyl, cyano, C1-C6-alkoxy or halogen- (C1-C6) -alkoxy; R4, R5, R6 and R7 are hydrogen or fluorine, and at least one of R4, R5, R6 and R7 is fluorine; R8 and R9 independently of each other are hydrogen or (C1-C6) -alkyl; m is 1, 2 or 3; n is 0, 1, 2 or 3; and p is 1 or 2; as well as its pharmaceutically acceptable salts.