ANTIBACTERIAL COMPOSITIONS WITH SYNERGISTIC EFFECT, DRUGS AND REMEDIES FOR DIGESTIVE DISEASES CONTAINING THE SAME, PROCESS FOR THE PRODUCTION THEREOF AND PREPARATIONS ASSOCIATED THEREWITH

摘要

Antibacterial compositions comprising (1) a rifamycinderivative represented by the formula (I) or its physiologically acceptablesalt, and (2) a proton pump inhibitor (a) or a bismuth preparation (b)wherein the components (1) and (2) are used in such amounts asproducing a synergistic effect against Helicobacter pylori, drugs andremedies for digestive organ diseases which contain the antibacterialcompositions, process for producing them, and pharmaceuticalpreparations related to the antibacterial compositions. Thecompositions can be administered to patients with digestive diseasescaused by infection of Helicobacter pylori in a smaller dose and at a loweradministration frequency as compared with conventional remedies.