LAK ACTIVITY-SCREENING MATERIALS CONTAINING LENTINUS EXTRACT OF EDODES MYCELIUM AND LAK ACTIVITY-SCREENING METHODS USING THE EXTRACT

摘要

It is an object of the present invention to provideinexpensive materials and methods for screeningimmunotherapeutic agents exhibiting antitumor and/oranticancer activity.The present invention provides a method fordetermining in vitro a material having an LAKactivity--enhancing effect suitable for a subject, comprising thesteps of:(a) collecting peripheral blood from the subject toprepare lymphocyte fractions,(b) preparing an LAK-induced sample and a controlsample by adding or not a screening material of the presentinvention to said lymphocyte fractions, and(c) measuring the LAK activities of said inducedsample and said control sample and comparing the results todetermine the in vitro LAK activity-enhancing effect of thescreening material for said subject.