METHODS FOR DETECTING MOLECULAR INTERACTIONS WITHIN CELLS USING COMBINATION OF INDUCIBLE PROMOTERS AND BIOSENSORS

摘要

The invention provides methods and reagents for identifying an agent, such as by screening a library of agents, that modulates the interaction of s an endogenous polypeptide and a biosensor polypeptide comprising a binding domain, a localization domain and a reporter domain all of which are operably linked to an inducible promoter.