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SYSTEMIC INSULIN-LIKE GROWTH FACTOR-1 THERAPY REDUCES DIABETIC PERIPHERAL NEUROPATHY AND IMPROVES RENAL FUNCTION IN DIABETIC NEPHROPATHY
SYSTEMIC INSULIN-LIKE GROWTH FACTOR-1 THERAPY REDUCES DIABETIC PERIPHERAL NEUROPATHY AND IMPROVES RENAL FUNCTION IN DIABETIC NEPHROPATHY
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机译:全身性胰岛素样生长因子-1疗法可减轻糖尿病性周围神经病变并改善糖尿病性肾病的肾功能
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摘要
The present invention provides methods of treatment of patients suffering from the complication of blood sugar disorders diabetic peripheral neuropathy and diabetic nephropathy by administration of IGF-1 via protein therapy or gene therapy It relates to methods of treating an individual having a diabetic disorder or a hyperglycemic disorder, comppsing administepng to the individual an effective amount of a DNA vector expressing IGF-1Eb or IGF-1Ec in vivo or an effective amount of the IGF-1Eb or IGF-1Ec protein in the early hyperalgesia stage or in patient that have advanced to the hyposensitivity stage
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