首页> 外国专利> USE OF T140 AND OPTIONALLY RETROCYCLIN-1 AS THERAPEUTIC AGENTS FOR THE TREATMENT OF M. TUBERCULOSIS INFECTIONS

USE OF T140 AND OPTIONALLY RETROCYCLIN-1 AS THERAPEUTIC AGENTS FOR THE TREATMENT OF M. TUBERCULOSIS INFECTIONS

机译:使用T140和可选的retrocyclin-1作为治疗性药物治疗结核分枝杆菌感染

摘要

The present invention is directed to the use of the peptide compound Arg-Arg-Trp-Cys- Tyr-Arg-Lys-Cys-Tyr-Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr- Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
机译:本发明涉及肽化合物Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr-Lys-Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH 2的用途用于预防和/或治疗癌症,自身免疫性疾病,纤维化疾病,炎性疾病,神经退行性疾病,感染性疾病,肺部疾病,心脏和血管疾病以及代谢性疾病的治疗剂。此外,本发明涉及药物组合物,其优选为冻干物或液体缓冲溶液或人工母乳制剂或母乳替代物形式,其包含肽Arg-Arg-Trp-Cys-Tyr-Arg-Lys-Cys-Tyr-Lys- Gly-Tyr-Cys-Tyr-Arg-Lys-Cys-Arg-NH 2任选地与至少一种药学上可接受的载体,冷冻保护剂,冻干保护剂,赋形剂和/或稀释剂一起。

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