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A METHOD TO ASSESS PROGNOSIS AND TO PREDICT THERAPEUTIC SUCCESS IN GYNECOLOGIC CANCER

机译:一种评估妇科肿瘤预后和治疗成功率的方法

摘要

The present invention is related to a method for predicting a clinical response of a patient suffering from or at risk of developing a gynecologic cancer towards a given mode of treatment, said method comprising the steps of : a) obtaining a biological sample from said patient; b) determining, on a non protein basis, the expression level of at least one gene encoding for a hormone receptor selected from the group comprising estrogen receptor, progesterone receptor and/or androgen receptor in said sample; c) comparing the pattern of expression level (s) determined in step b) with one or several reference pattern (s) of expression levels; and d) predicting therapeutic success for said given mode of treatment in said patient from the outcome of the comparison in step c).
机译:本发明涉及一种预测患有妇科癌症或有患妇科癌症风险的患者对给定治疗方式的临床反应的方法,所述方法包括以下步骤:a)从所述患者获得生物样品; b)以非蛋白质为基础,确定所述样品中至少一种编码选自包括雌激素受体,孕激素受体和/或雄激素受体的激素受体的基因的表达水平; c)将步骤b)中确定的表达水平的模式与一种或几种表达水平的参考模式进行比较; d)根据步骤c)中的比较结果预测所述患者中所述给定治疗方式的治疗成功。

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