EXTRACT OF STEREOCAULON ALPINUM HAVING INHIBITORY EFFECT OF PROTEIN TYROSINE PHOSPHATASE 1B ACTIVITY AND USNIC ACID DERIVATIVES ISOLATED THEREFROM

摘要

Disclosed are antarctic lichen stereocaulon alpinum extract and a usnic acid derivative isolated therefrom that have an activity inhibiting activity of the protein tyrosine dephosphorylase 1B. Stereocaulon alpinum extract according to the present invention and the usnic acid derivative isolated therefrom have a hypoglycemic effect on hyperglycemia, a major symptom of diabetes. ; Stereocaulon alpinum, protein tyrosine dekinase 1B (PTP1B)