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A METHOD FOR THE PREVENTION AND TREATMENT OF ESSENTIAL TREMOR BY REGULATING A1G T-TYPE CALCIUM CHANNEL OR BY T-TYPE CALCIUM CHANNEL BLOCKERS
A METHOD FOR THE PREVENTION AND TREATMENT OF ESSENTIAL TREMOR BY REGULATING A1G T-TYPE CALCIUM CHANNEL OR BY T-TYPE CALCIUM CHANNEL BLOCKERS
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机译:调节A1G T型钙离子通道或T型钙离子通道阻滞剂预防和治疗根本性前躯体的方法
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摘要
The present invention relates to a method for the prevention and treatment of essential tremor by blocking alpha1G T-type calcium channel, a preventive and therapeutic agent for essential tremor containing the alpha1G T-type calcium channel blocker as an active ingredient, and a screening method of a preventive and therapeutic agent for essential tremor by investigating alpha1G T-type calcium channel blocking activity. More precisely, the present invention relates to a method for the prevention and treatment of essential tremor by using alpha1G T-type calcium channel blocker, for which the inventors confirmed that the alpha1G T-type calcium channel knock out mice (alpha1G -/-) had resistance against essential tremor and when the T-type channel blocker was administered to the wild type mice (alpha1G +/+), they gained resistance against essential tremor.
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