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METHOD AND SYSTEM FOR EXTRACTING AND DISPLAYING INTERACTION NETWORKS BETWEEN PROTEINS AND SIGNAL PATHWAYS BY MAPPING PROTEIN-PROTEIN INTERACTION AND SIGNAL PATHWAY INFORMATION

机译:映射蛋白质-蛋白质相互作用与信号通路信息,提取和显示蛋白质与信号通路相互作用网络的方法和系统

摘要

The present invention, between the protein and protein of the relationship in relation to a kind of intersection in export between protein and signal transduction pathway, to a kind of mapping (mapping) of the interaction between information transmission path information of the method and system shown. The present invention provides a schematic diagram, shows the function with the protein of interested albumen PPI (protein interaction) components interaction; The single protein and pioneer's interactive relation of a function are provided, searching includes the transmission path first is that the protein of (navigator) component; The interaction distance of end from the existing protein on interested (interaction distance) connector of multiple protein and signal transduction pathway provides the function of indicating path (path-connector) component; Transmitting label (path-label) component is used to provide the interaction of multiple protein and shows the position of the last protein in caused signal pathway and the ability of frequency; That multiple protein is searched along transmission path, it is respectively related with the number of interaction distance (interaction distance), the signal of starting protein and path transmission path, transmission path, in the last protein stock priority to statistical nature path list (path-Li Site) component; User with more accurate reliable information, which can be provided to, improves biological species (organism), type of interaction (interaction type), interaction detection method (interaction detection method), information (provides the number of DB, relevant file, using filter function, for example, interaction detection method number filter (filter) component) number.
机译:本发明中,蛋白质与蛋白质之间的关系与蛋白质与信号转导途径之间的输出相交有关,涉及一种信息(方法)和系统的信息传递路径信息之间的相互作用的映射(作图) 。本发明提供了示意图,示出了与感兴趣的蛋白的蛋白的蛋白PPI(蛋白质相互作用)成分相互作用的功能;提供功能的单一蛋白质与先驱者的相互作用关系,搜索首先包括传播途径是(导航剂)成分的蛋白质;末端与现有蛋白质在多种蛋白质感兴趣的连接体上的相互作用距离(相互作用距离)与信号转导通路具有指示路径(path-connector)成分的功能;传输标记(path-label)成分用于提供多种蛋白质的相互作用,并显示最后蛋白质在引起信号通路中的位置和频率的能力;沿传输路径搜索多个蛋白质,分别与相互作用距离(interaction distance)的数目,起始蛋白质的信号和路径的传输路径,传输路径有关,最后一个蛋白质库存中优先于统计性质的路径列表(path -Li Site)组件;为用户提供更准确可靠的信息,可以向其提供信息,以改善生物种类(生物),相互作用类型(相互作用类型),相互作用检测方法(相互作用检测方法),信息(提供DB的数量,相关文件,使用过滤器功能,例如,交互检测方法编号过滤器(filter)的组成部分)编号。

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