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METHOD AND SYSTEM FOR EXTRACTING AND DISPLAYING INTERACTION NETWORKS BETWEEN PROTEINS AND SIGNAL PATHWAYS BY MAPPING PROTEIN-PROTEIN INTERACTION AND SIGNAL PATHWAY INFORMATION
METHOD AND SYSTEM FOR EXTRACTING AND DISPLAYING INTERACTION NETWORKS BETWEEN PROTEINS AND SIGNAL PATHWAYS BY MAPPING PROTEIN-PROTEIN INTERACTION AND SIGNAL PATHWAY INFORMATION
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机译:映射蛋白质-蛋白质相互作用与信号通路信息,提取和显示蛋白质与信号通路相互作用网络的方法和系统
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摘要
The present invention, between the protein and protein of the relationship in relation to a kind of intersection in export between protein and signal transduction pathway, to a kind of mapping (mapping) of the interaction between information transmission path information of the method and system shown. The present invention provides a schematic diagram, shows the function with the protein of interested albumen PPI (protein interaction) components interaction; The single protein and pioneer's interactive relation of a function are provided, searching includes the transmission path first is that the protein of (navigator) component; The interaction distance of end from the existing protein on interested (interaction distance) connector of multiple protein and signal transduction pathway provides the function of indicating path (path-connector) component; Transmitting label (path-label) component is used to provide the interaction of multiple protein and shows the position of the last protein in caused signal pathway and the ability of frequency; That multiple protein is searched along transmission path, it is respectively related with the number of interaction distance (interaction distance), the signal of starting protein and path transmission path, transmission path, in the last protein stock priority to statistical nature path list (path-Li Site) component; User with more accurate reliable information, which can be provided to, improves biological species (organism), type of interaction (interaction type), interaction detection method (interaction detection method), information (provides the number of DB, relevant file, using filter function, for example, interaction detection method number filter (filter) component) number.
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