首页> 外国专利> METHOD OF DIFFERENTIAL DIAGNOSTICS OF PROFESSIONAL SENSORINEURAL DEAFNESS FROM SENSORINEURAL DEAFNESS OF NON-PROFESSIONAL GENESIS

METHOD OF DIFFERENTIAL DIAGNOSTICS OF PROFESSIONAL SENSORINEURAL DEAFNESS FROM SENSORINEURAL DEAFNESS OF NON-PROFESSIONAL GENESIS

机译:非专业基因型感官神经性聋的鉴别诊断方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to field of medicine, namely, to otolaryngology and professional pathology. Electroencephalography (EEG) with registration of long-latent acoustic induced potentials (LAIP), electroneuromyography (ENMG), algesimetry are performed and diagnostic coefficients F1 and F2 are calculated by formulas F1=-5.00-2.97·A,+5.67·A2-0.69·A3+1.52·A4+1.19·A5-0.99·A6-2.6··A7+3.21·A8-2.13·A9+0.98·A10-1.97·A11-3.59·A12; F2=-14.61+8.55-A1-6.67·A2+3.01·A3-2.16·A4-1.96·A5+3.09·A6+2.06··A7-4.3·A8+3.44·A9-1.7-A10+2.86·A11+2.43·A12, where F1 - diagnostic coefficient for professional sensorineural deafness, F2 - diagnostic coefficient for sensorineural deafness of non-professional character; -5.00 and -14.61 - constants, 2.97; 5.67; 0.69; 1.52; 1.19; 0.99; 2.6; 3.21; 2.13; 0.98; 1.97; 3.59; 8.55; 6.67; 3.01; 2.16; 1.96; 3.09; 2.06; 4.3; 3.44; 1.7; 2.86; 2.43 - discriminatory coefficients; A1 - motor rate in distal part of tibial nerve in m/sec; A2 - index of algesimetry on second phalanx of second finger of right hand in mm; A3 -sensory rate in distal part of tibial nerve in m/sec; A4 - index of latency P1 of LAIP in left temporal led in msec; A5 - index of between-peak interval N 11-13 of "ССВП" in msec; A6 - motor rate on section wrist-elbow of median nerve in m/sec; A7 - index of amplitude P1N1 of LAIP in left temporal lead in mcV; A8 - index of latency N2 of LAIP in right temporal lead in msec; A9 - index of latency of P2 of LAIP in right temporal lead in msec; A10 - presence of irritative changes on EEG, absent - 1, present - 0; A11 - sensory rate on ulner nerve in msec; A12 - index of residual latency of median nerve in msec. If value F1 is larger or equal F2, professional sensoruneural deafness is diagnosed, if F1 is less than F2, sensoruneural deafness of non-professional genesis is diagnosed.;EFFECT: increase of reliability of differential diagnostics, which is achieved due to examination of whole sensorineural complex.;1 tbl, 3 ex
机译:技术领域本发明涉及医学领域,即耳鼻咽喉科和专业病理学。进行脑电图(EEG)和长潜伏声诱发电位(LAIP)的配准,电子肌电图(ENMG),法分析法,并通过以下方法计算诊断系数F 1 和F 2 公式F 1 =-5.00-2.97·A,+ 5.67·A 2 -0.69·A 3 + 1.52·A 4 + 1.19·A 5 -0.99·A 6 -2.6··A 7 + 3.21·A 8 < /Sub>-2.13·A9+0.98·A10-1.97·A11-3.59·A12; F 2 =-14.61 + 8.55-A 1 -6.67·A 2 + 3.01·A 3 -2.16 ·A 4 -1.96·A 5 + 3.09·A 6 + 2.06··A 7 -4.3· A 8 + 3.44·A 9 -1.7-A 10 + 2.86·A 11 + 2.43·A < Sub> 12 ,其中F 1 -专业感音神经性聋的诊断系数,F 2 -非专业感音神经性聋的诊断系数; -5.00和-14.61-常数2.97; 5.67; 0.69; 1.52; 1.19; 0.99; 2.6; 3.21; 2.13; 0.98; 1.97; 3.59; 8.55; 6.67; 3.01; 2.16; 1.96; 3.09; 2.06; 4.3; 3.44; 1.7; 2.86; 2.43-鉴别系数; A 1 -胫神经远端运动速度,单位m / sec; A 2 -右手第二指的第二指骨的法术指数,单位为mm;胫神经远端A 3 -感觉速率,m / sec; A 4 -左颞叶LAIP潜伏期P1指标,以毫秒为单位A 5 -“ССВП”的峰间间隔N 11-13的索引,以毫秒为单位; A 6 -正中神经节腕肘的运动速度,单位m / sec; A 7 -左颞导联处LAIP振幅P1N1的指标,以mcV为单位; A 8 -右颞导联的LAIP延迟N2的毫秒数; A 9 -LAIP P2在右颞导联的潜伏期的毫秒数; A 10 -脑电刺激性变化的存在,不存在-1,存在-0; A 11 -毫秒神经对尺神经的感觉速率; A 12 -正中神经残留潜伏期的毫秒数。如果F 1 值大于或等于F 2,则诊断为专业性耳神经性耳聋,如果F 1 小于F 2 < / sub>,诊断出非专业性的感音神经性耳聋;效果:通过检查整个感音神经复合体,可以提高鉴别诊断的可靠性。1tbl,3 ex

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