首页> 外国专利> METHOD FOR PREPARING ALBUTEROL AND IPRATROPIUM INHALATION SOLUTION FOR RELIEVING SYMPTOM OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, AND PREPACKAGE TREATMENT SYSTEM

METHOD FOR PREPARING ALBUTEROL AND IPRATROPIUM INHALATION SOLUTION FOR RELIEVING SYMPTOM OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, AND PREPACKAGE TREATMENT SYSTEM

机译:缓解慢性阻塞性肺疾病症状的阿布特罗和白IP吸入溶液的制备方法及预包装治疗系统

摘要

PROBLEM TO BE SOLVED: To provide a method for preparing a bronchodilator inhalation solution for relieving the bronchospasm of patients suffering from chronic obstructive pulmonary disease.;SOLUTION: The method comprises preparing an inhalation solution provided in the form of a unit-dose receptacle containing a single-unit-dose inhalation solution, prepackaged, stable, premeasured and premixed for the purpose of inducing the bronchodilation or relieving the bronchospasm of patients suffering from chronic obstructive pulmonary disease. Specifically, the method includes: (a) a step of putting clean water into a stainless steel tank at 18-25°C; (b) a step of adding into the tank an acid, an infiltrative adjuster and at least each treatment-effective amount of albuterol sulfate and ipratropium bromide while mixing them together into a solution to form the objective inhalation solution, which is then put into the tank; and (c) a step of packing each of administration receptacles with 3 mL of the inhalation solution so that each of the receptacles contains presterilized unit-dose albuterol and ipratropium bromide.;COPYRIGHT: (C)2011,JPO&INPIT
机译:解决的问题:提供一种制备用于缓解患有慢性阻塞性肺疾病的患者的支气管痉挛的支气管扩张剂吸入溶液的方法。解决方案:该方法包括制备以单位剂量容器形式提供的吸入溶液,该容器包含预先包装,稳定,预先计量和预先混合的单剂量吸入溶液,用于诱导患有慢性阻塞性肺疾病的患者支气管扩张或缓解支气管痉挛。具体地,该方法包括:(a)将纯净水放入18-25℃的不锈钢罐中的步骤; (b)将酸,渗透调节剂和至少每种治疗有效量的硫酸沙丁胺醇和异丙托溴铵混合到溶液中以形成目标吸入溶液的步骤,该溶液应加入到罐中坦克; (c)在每个给药容器中装满3 mL吸入溶液的步骤,以使每个容器中都包含预先灭菌的单位剂量沙丁胺醇和异丙托溴铵。;版权:(C)2011,JPO&INPIT

著录项

  • 公开/公告号JP2010235617A

    专利类型

  • 公开/公告日2010-10-21

    原文格式PDF

  • 申请/专利权人 DEY LP;

    申请/专利号JP20100128163

  • 发明设计人 CHAUDRY IMTIAZ;BANERJEE PARTHA;

    申请日2010-06-03

  • 分类号A61K31/46;A61K31/137;A61K9/72;A61K47/02;A61K47/10;A61K47/26;A61K47/18;A61P11/00;A61P43/00;

  • 国家 JP

  • 入库时间 2022-08-21 19:06:01

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