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The medical device which possesses the organism attack characteristic layer for discharging the remedy medicine
The medical device which possesses the organism attack characteristic layer for discharging the remedy medicine
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机译:具有用于排出药物的生物攻击特征层的医疗装置
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摘要
According to an aspect of the present invention, medical devices are provided which comprise: (a) a substrate, (b) an inner bioerodable polymeric layer over the substrate that comprises (i) 80 wt % or more of an amorphous biodegradable polymeric component and (ii) 20 wt % or less of a therapeutic agent component, and (c) an outer bioerodable polymeric layer over the inner bioerodable polymeric layer that comprises (i) 80 wt % or more of an amorphous biodegradable polymeric component and (ii) 20 wt % or less of a therapeutic agent component. The compositions of the inner and outer layers differ such that the outer layer has a bioerosion rate that is faster than that of the inner layer.
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