How to fill in the amphoteric liposomes and method in amphoteric liposomes or prescribe improvement on the amphoteric liposomes, amphoteric liposomes

摘要

An amphoteric liposome composed of a mixture of lipids, said mixture comprising a cationic amphiphile, an anionic amphiphile and optionally one or more neutral amphiphiles. Also disclosed are methods of predicting the fusogenicity of an amphoteric liposome at a given pH, formulating an amphoteric liposome and loading an amphoteric liposome with a cargo moiety.