DOPPLER AND IMAGE GUIDED DEVICE FOR NEGATIVE FEEDBACK PHASED ARRAY HIFU TREATMENT OF VASCULARIZED LESIONS

摘要

A noninvasive technique that can be used to deny blood flow to a particular region of tissue, without the inherent risks associated with invasive procedures such as surgery and minimally-invasive procedures such as embolization. Blood flow in selected portions of the vasculature can be occluded by selectively treating specific portions of the vasculature with high intensity focused ultrasound (HIFU), where the HIFU is targeted Doppler ultrasound data, and a duration of the therapy is automatically controlled using a negative feedback loop provided by Doppler ultrasound data collected during the HIFU therapy. A portion of the vasculature providing blood flow to the undesired tissue is selected by a clinician, or automatically selected based on Doppler data, and HIFU is administered to the selected portion of the vasculature to occlude blood flow through that portion of the vasculature.