首页>
外国专利>
Mutants of Human App and Their Use for the Production of Transgenice Animals
Mutants of Human App and Their Use for the Production of Transgenice Animals
展开▼
机译:人类应用的突变体及其在转基因动物生产中的应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
A modified amyloid precursor protein can be expressed from a DNA construct comprising an APP DNA sequence, or a fragment or artificial substrate thereof, encoding the mutation I45W, I45Y V46W or V46Y (numbering relative to A4CT); the use of the DNA construct in the generation of cell lines or transgenic animals and the use of these proteins or such transgenic animals in the diagnosis of Alzheimer's Disease and screening putative drugs against Alzheimer's Disease are also described.
展开▼