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Natriuretic peptides and placenta growth factor levels for risk stratification

机译:利钠肽和胎盘生长因子水平用于危险分层

摘要

The present invention relates to a method for determining a risk whether an individual will suffer from a cardiovascular adverse event as a consequence of cardiac stress testing, comprising the steps of (a) measuring, preferably in vitro, the level of placenta growth factor, wherein (b) if the level of the placenta growth factor is at least increased, then the individual is at least at risk of suffering from an adverse event as a consequence of cardiac stress testing. In a further embodiment, additionally another marker is measured, particularly a natriuretic peptide, most particularly NT-proBNP. The present invention allows to stratify patients according to the environment and conditions under which cardiac stress testing should be carried out.
机译:本发明涉及一种用于确定个体是否由于心脏压力测试而患有心血管不良事件的风险的方法,该方法包括以下步骤:(a)优选在体外测量胎盘生长因子的水平,其中(b)如果胎盘生长因子的水平至少增加,则该个体至少因心脏压力测试而有遭受不良事件的风险。在另一个实施方案中,另外测量了另一种标志物,特别是利钠肽,最特别是NT-proBNP。本发明允许根据应当进行心脏压力测试的环境和条件对患者进行分层。

著录项

  • 公开/公告号US7820373B2

    专利类型

  • 公开/公告日2010-10-26

    原文格式PDF

  • 申请/专利权人 GEORG HESS;ANDREA HORSCH;

    申请/专利号US20080186958

  • 发明设计人 ANDREA HORSCH;GEORG HESS;

    申请日2008-08-06

  • 分类号C12Q1/00;

  • 国家 US

  • 入库时间 2022-08-21 18:50:53

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