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Therapeutic compositions to enhance the effect of Antibody Therapy against the epidermal growth factor receptor

机译:增强针对表皮生长因子受体的抗体疗法效果的治疗组合物

摘要

1. - a Therapeutic composition useful in the treatment of cancer which comprises the simultaneous or Sequential Administration of an Antibody against the EGF receptor and one or more types of interferons 1.2.The therapeutic Composition of claim 1, characterized in that it comprises an Antibody against the EGF receptor, interferon and an appropriate carrier for Administration via intravenosa.3. - Therapeutic Composition of claims 1 and 2, wherein the Monoclonal antibody against the EGF receptor is a Chimeric Antibody.The therapeutic Composition of claim 3 wherein the monoclonal antibody against the EGF receptor is an Antibody humanizado.5. - Therapeutic Composition of claim 4 wherein the monoclonal antibody against the EGF receptor is the ancient RPO Humanized HR3 produced by the cell line with the number of 951110101.6 deposit.The therapeutic Composition of claim 1 and 2, wherein the Interferon Type is 1.7 Therapeutic Composition of claim 6 wherein the interferon is INF - - humano.8. Therapeutic Composition of claim 7 wherein the R Recombinant human interferon is INF -. 9.A Therapeutic composition characterized in that it comprises the HR3 monoclonal antibody against the EGF receptor produced by the cell line with no deposit. 951110101 and recombinant human interferon INF -.
机译:1.用于治疗癌症的治疗组合物,其包括同时或顺序施用针对EGF受体的抗体和一种或多种类型的干扰素。1.2。权利要求1的治疗组合物,其特征在于,其包括针对EGF受体的抗体。 EGF受体,干扰素和通过静脉内给药的合适载体3。 -权利要求1和2的治疗组合物,其中所述针对EGF受体的单克隆抗体是嵌合抗体。4.权利要求3的治疗组合物,其中所述针对EGF受体的单克隆抗体是抗体humanizado.5。 -权利要求4的治疗组合物,其中所述抗EGF受体的单克隆抗体是细胞系产生的古老的RPO人源化HR3,其保藏数目为951110101.6。3.权利要求1和2的治疗组合物,其中干扰素类型为1.7。 7.根据权利要求6的方法,其中干扰素是INF-人抗体。 8,权利要求7的治疗组合物,其中R重组人干扰素是INF-。 9.一种治疗组合物,其特征在于它包含针对由细胞系产生的EGF受体的HR3单克隆抗体,没有沉积物。 951110101和重组人干扰素INF-。

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