NEW DERIVATIVES 6-TRIAZOLPIRIDINSULPHANIL-BENZOTHIAZOLE OUR APPLICATIONS -BENZIMIDAZOLE, METHOD OF THEIR RECEIVING, APPLICATION OF THEIR AS A MEDICINE, PHARMACEUTICAL COMPOSITIONS AND NOVA NOVA.

摘要

The invention relates to new products of formula (I), in which it denotes a single or double bond; Ra is H, Gal, alkoxy, O-cycloalkyl, heteroalkyl, phenyl, NHCOalk, NHCOcycloalkus or NR1R2; X is S, SO or SO; A means NH or S; W is H, alkyl or COR, where R is cycloalkyl; alkyl is optionally substituted with NR3R4, alkoxy, hydroxy, phenyl, heteroaryl, or heterocycloalkyl; alkoxy is optionally substituted with NR3R4, i.e. means the radical-O- (CH) n-NR3R4, the radical O-phenyl or O- (CH) n-phenyl, where phenyl is optionally substituted and n = 1-4; or the radical NR1R2; R1 is H or alkyl and R2 is H, cycloalkyl or alkyl; R3 and R4 are H, alkyl, cycloalkyl, heteroaryl or phenyl; R1, R2 and / or R3, R4 form with N a cycle, optionally containing O, S, N and / or NH; all heterocycloalkyl, heteroaryl, phenyl and cyclic radicals being optionally substituted; these products, in all isomeric forms, and their salts are useful as pharmaceuticals, in particular as MET inhibitors.