METHODS FOR PREDICTING RISK FOR DEVELOPING ADOLESCENT IDIOPATHIC SCOLIOSIS (AIS) IN HUMANS AND KITS FOR SAID METHOD AND METHOD FOR SELECTING COMPOUNDS USEFUL IN THE TREATMENT OF AIS

摘要

A method of stratifying a subject having adolescent idiopathic scoliosis (AIS) comprising: providing a cell sample isolated from the subject; detecting Paired-like homeodomain transcription factor 1 (Pitxi ) expression in the cell sample; whereby the results of the detecting step enables the stratification of the subject having AIS as belonging to an AIS subclass.