POLYMORPHISMS OF CHROMOSOME 9 IMPLICATED IN PREMATURE CANITIES

摘要

The invention relates to the use of at least one of the 4 SNP markersrs306534, rs3739902, rs575916 and rs365297 for carrying out a diagnosis, aprocess for diagnosing a predisposition to premature canities, the use of ameans for determining the alleles of the 4 markers with a view to a diagnosisand a kit for the diagnosis, a process for the diagnosis of a predispositionto premature canities based on the haplotype defined by the markers rs3739902,rs2583805 and rs377090 and the use of at least one polynucleotide fragmentcomprising at least 18 consecutive nucleotides, the sequence of whichcorresponds to all or part of the region in a non-human mammal homologous tothat of the human chromosome 9 defined by the SNP markers rs306534 andrs365297 for the diagnosis of a predisposition to premature canities in saidmammal.