PARKINSON'S DISEASE MODEL MOUSE, PROCESS FOR PRODUCING THE MOUSE, AND SCREENING METHOD AND EVALUATION METHOD FOR THERAPEUTIC AGENT FOR PARKINSON'S DISEASE EACH USING THE MOUSE

摘要

Disclosed are: a Parkinson's disease model mouse which can develop the symptoms of Parkinson's disease reliably in the early stage; a process for producing the mouse; and a screening method and an evaluation method for a therapeutic agent for Parkinson's disease, each of which utilizes the mouse. The Parkinson's disease model mouse is characterized in that a gene encoding parkin is inactivated and IRP2 is expressed specifically in nerve cells.