The invention relates to a sensor array for detecting the presence of a target, where a target is detected based on a detection of a surface plasmon resonance (SPR). The sensor array (30) comprises a carrier substrate (31), and a plurality of nano-sized particles (32) disposed on the carrier substrate. The surface plasmon resonance (SPR) for each of the nano-sized particles is correlated to a structural parameter of the nano-sized particles or group of nano-sized particles. The structural parameter and thereby the surface plasmon resonance is varied in a pre-defined way in at least a first area of the carrier substrate. The target is detected based on detecting intensity variations in the radiation resulting from the sensor array, the intensity variations being correlated to the pre-defined variation in the structural parameter. In embodiments, the sensor array may be a bio-sensor for the detection of bio-molecules.
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