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PRODUCTION OF PEPTIDES AND PROTEINS BY ACCUMULATION IN PLANT ENDOPLASMIC RETICULUM-DERIVED PROTEIN BODIES

机译:植物内质网蛋白体的积累法生产肽和蛋白

摘要

A nucleic acid molecule is disclosed as containing a first nucleic acid sequence comprising a nucleotide sequence that encodes γ-zein protein, or a fragment thereof capable of directing and retaining a protein towards the endoplasmic reticulum (ER) of a plant cell; a second nucleic acid sequence containing a nucleotide sequence that encodes an amino acid sequence that is specifically cleavable by enzymatic or chemical means; and a third nucleic acid sequence containing the nucleotide sequence that encodes a peptide or protein of interest. Methods of using this nucleic acid molecule for transforming host plant cells and producing the peptide or protein of interest are also disclosed.;COPYRIGHT KIPO & WIPO 2010
机译:公开了一种核酸分子,其包含第一核酸序列,该第一核酸序列包含编​​码γ-玉米醇溶蛋白的核苷酸序列或其片段,该核苷酸序列能够将蛋白质引导并保持朝向植物细胞的内质网(ER);第二核酸序列,其包含核苷酸序列,该核苷酸序列编码可通过酶或化学方式特异性切割的氨基酸序列;第三核酸序列,其包含编码目的肽或蛋白质的核苷酸序列。还公开了使用该核酸分子转化宿主植物细胞并产生目的肽或蛋白质的方法。COPYRIGHT KIPO&WIPO 2010

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