TRIFOLIATE ORANGE EXTRACTS HAVING ANTI INFLAMMATION ACTIVITIES, COUMARIN DERIVATIVES HAVING ANTI INFLAMMATION ACTIVITIES COMPRISING 7-GERANYLOXY COUMARIN AND ANTI INFLAMMATION MEDICAMENTS COMPRISING THE TRIFOLIATE ORANGE EXTRACTS OR COUMARIN DERIVATIVES COMPRISING 7-GERANYLOXY COUMARIN

摘要

PURPOSE: A Poncirus trifoliate RAF. Extract and a method or manufacturing the same are provided to isolated anti-inflammatory 7-geranyloxy coumarins and to treat inflammation. CONSTITUTION: A method for extracting Poncirus trifoliate RAF. comprises: a step of washing and drying Poncirus trifoliate RAF.; a step of adding 2-4L of ethanol to 500g of Poncirus trifoliate RAF. and stirring at 250-350 rpm and room temperature for 20 to 40 hours; and a step of decompressing the extract to remove solvent to obtain solid extract. The Poncirus trifoliate RAF. extract is isolated through pre-liquid chromatography.