Method of purifying p-coumaric acid from Sasa quelpaertensis Nakai, and cosmeceuticals and pharmaceutical composition using the purified p-coumaric acid

摘要

The present invention Jeju Sasa ( Sasa quelpaertensis of the active ingredient from Nakai) p - coumarin acid ( p manner as to purify the -coumaric acid) Refined p - coumarin acid ( p -coumaric acid) relates to functional cosmetics and pharmaceutical compositions including, more specifically, the purification process is the Jeju Sasa ( Sasa quelpaertensis Nakai) ethanol (ethanol) in 10 to 70 of extraction temperature in the extraction steps; Concentrate produced by preparing a concentrated under reduced pressure to extract liquid obtained from the extraction step; Fraction was fractionated to obtain a fraction of the concentrate with a solvent, and concentrated under a reduced pressure; The eluent was separated by filtration to obtain a fraction eluted with time, the eluting solution to obtain a dissolved solution was prepared by dissolving the eluate in ethanol (ethanol); And the eluted solution by ethanol (ethanol) recrystallization recrystallization step to obtain the crystals comprising the p - coumarin acid ( p -coumaric acid) and purification The same purification tablets and p - coumarin acid ( p -coumaric acid) as the active ingredient, and the effectiveness minutes tyrosinase (tyrosinase) and alpha - MSH (-MSH) will block the activity of a functional cosmetic composition and a pharmaceutical composition for inhibiting the production of melanin (melanin).