The kit for diagnosing mixed malaria infection of Plasmodium vivax and Plasmodium falciparum comprising specific antibodies against lactate dehydrogenase of Plasmodium vivax and Plasmodium falciparum

摘要

The present invention relates to a kit for diagnosing malaria including a monoclonal antibody specific to Plasmodium vivax LDH, a monoclonal antibody specific to Plasmodium falciparum LDH, and a monoclonal antibody simultaneously specific to Plasmodium vivax LDH and Plasmodium falciparum LDH and a method of diagnosing mixed malaria infection using the same. The kit is the first rapid and convenient diagnosis kit in the world, which can discriminate the kinds of infected malaria and diagnose mixed infection of P. vivax and P. falciparum with high specificity and sensitivity. Further, the present invention discloses monoclonal antibodies specifically binding to P. vivax and P. falciparum LDHs used in the kit, and hybridoma producing the same. Finally, the present invention also discloses a kit for diagnosing malaria including a monoclonal antibody specific to P. vivax.