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METHOD OF LOCAL TUMOR DESTRUCTION BY MEANS OF SHF HEATING OF MAGNETIC NANOPARTICLES

机译:磁性纳米粒子SHF加热的局部肿瘤消融方法

摘要

FIELD: medicine.;SUBSTANCE: magnet-controlled nanoparticles from magnetite Fe3O4 in physiological solution are used. Maximal size of nanoparticles does not exceed 100 nm, particles have coating from biologically compatible material. Created is space local constant magnetic field which has configuration commensurable in volume with tumor and having intensity which does not exceed 0.1 T. When maximal concentration of nanoparticles in tumor is obtained it is irradiated with pulse SHF radiation with frequency in range 2.4 GHz - 10 GHz.;EFFECT: method allows to destroy locally deeply located neoplasms with minimal destruction of surrounding healthy tissues, allows to perform operation without general anesthesia.;5 cl, 4 dwg
机译:领域:药物;物质:使用生理溶液中磁铁矿Fe 3 O 4 的磁铁控制纳米颗粒。纳米粒子的最大尺寸不超过100 nm,粒子具有生物相容性材料制成的涂层。产生的空间局部恒定磁场的结构与肿瘤的体积相当,强度不超过0.1T。当肿瘤中的纳米颗粒达到最大浓度时,用频率在2.4 GHz-10 GHz范围内的脉冲SHF辐射进行辐照。效果:该方法可以破坏局部深处的肿瘤,而对周围健康组织的破坏最小,可以进行手术而无需全身麻醉。; 5 cl,4 dwg

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