Food material useful for prevention and improvement of metabolic bone disease and preventive and therapeutic drug for metabolic bone disease comprising active ingredients of the material

摘要

This invention relates to drinks and foods having osteogenetic function, each of which comprises as an active ingredient an effective amount of a culture of a propionic acid bacterium and/or a lactic acid bacterium, said culture containing 2-amino-3-carboxy-1,4-naphthoquinone; and preventives and/or remedies for metabolic bone diseases, each of which comprises as an active ingredient a naphthoquinone compound selected from the group consisting of 2-amino-3-carboxy-1,4-naphthoquinone, 1,4-naphthoquinone, 2-hydroxy-1,4-naphthoquinone, 2,3-dichloro-1,4-naphthoquinone, 5-hydroxy-1,4-naphthoquinone, 8-hydroxy-1,4-naphthoquinone, 2-( alpha -hydroxy- delta -methylpentenyl)-5,8-dihydroxy-1,4-naphthoq uinone and salts thereof. These cultures and naphthoquinones promote bone metabolism and increase bone mass and bone strength.