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Triacylglycerol lipase family LLG polypeptides, compositions, methods for use in enzymatic hydrolysis, protein and gene therapy

机译:三酰基甘油脂肪酶家族LLG多肽,组合物,用于酶促水解,蛋白质和基因治疗的方法

摘要

The present invention relates to LLG polypeptides, which are polypeptides of the triacylglycerol lipase family, and fragments thereof, antibodies against such polypeptides, nucleic acids encoding such polypeptides, and antisense nucleic acids derived from such nucleic acids. The invention relates also to therapeutic compositions and methods comprising the above. In addition, the invention relates to the preparation of LLG polypeptides using recombinant technology and to the use of LLG polypeptides to screen for agonists and antagonists thereof.
机译:本发明涉及作为三酰甘油脂肪酶家族的多肽的LLG多肽及其片段,针对这种多肽的抗体,编码该多肽的核酸以及衍生自该核酸的反义核酸。本发明还涉及包含上述物质的治疗组合物和方法。另外,本发明涉及使用重组技术制备LLG多肽的方法,并且涉及使用LLG多肽筛选其激动剂和拮抗剂的用途。

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