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Gene 62 of attenuated varicella virus Oka strain and identification method of attenuated live varicella vaccine virus strain using this gene 62
Gene 62 of attenuated varicella virus Oka strain and identification method of attenuated live varicella vaccine virus strain using this gene 62
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机译:减毒水痘病毒冈株的基因62及使用该基因的减毒活水痘疫苗病毒株的鉴定方法
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摘要
The present application provides the gene 62 of Oka vaccine virus, which comprises at least with the following base substitutions (a) to (d) in the nucleotide sequence of SEQ ID No. 1: (a) the base A at position 2110 is G; (b) the base A at position 3100 is G; (c) the base T at position 3818 is C; and (d) the base A at position 4006 is G, and a method for identifying the Oka vaccine virus and an attenuated varicella-zoster virus strain acceptable as virus strain for live attenuated varicella vaccine, by using the gene 62.
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机译:本申请提供了Oka疫苗病毒的基因62,其在SEQ ID No.1的核苷酸序列中至少包含以下碱基取代(a)至(d):(a)2110位的碱基A为G ; (b)位置3100处的基座A为G; (c)位置3818处的底T为C; (d)4006位的碱基A为G,以及通过使用基因62来鉴定可作为活的减毒水痘疫苗的病毒株的Oka疫苗病毒和减毒的水痘带状疱疹病毒株的方法。
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