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IMPLANTABLE NEUROENDOPROSTHETIC SYSTEM, A METHOD OF PRODUCTION THEREOF AND A METHOD OF RECONSTRUCTIVE NEUROSURGICAL OPERATION
IMPLANTABLE NEUROENDOPROSTHETIC SYSTEM, A METHOD OF PRODUCTION THEREOF AND A METHOD OF RECONSTRUCTIVE NEUROSURGICAL OPERATION
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机译:植入式神经内科假体系统,其生产方法和重建性神经外科手术方法
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摘要
Intended for the use in neurosurgery and organ tissue engineering to replace defects of nervous tissue of a mammal brain and spinal cord (B&SC) in reconstructive neurosurgical operations, a tissue-replaceable artificial cell-biopolymer neuroendoprosthetic system (ACBP NEPS) for surgical plasty of defects of nervous tissue of B&SC, stimulating regeneration and growth of damaged axons of neural cells, comprises an elastic cell-biopolymer biologically active mass, produced from a heterogeneous collagen-containing matrix for implantation, and a biocomposition of cell preparations of various types of autologous cells of a patient. Also disclosed are a method of producing the ACBP NEPS, which provides for perfusion of the biocomposition of the cell preparations of various types of autologous cells of a patient into a heterogeneous collagen-containing matrix for implantation, and a method of reconstructive neurosurgical operation comprising implantation of the ACBP NEPS into a defect of neural tissue.
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