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THE ROLE OF IL17RD AND THE IL23-1L17 PATHWAY IN CROHN'S DISEASE
THE ROLE OF IL17RD AND THE IL23-1L17 PATHWAY IN CROHN'S DISEASE
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机译:IL17RD和IL23-1L17通路在克罗恩病中的作用。
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摘要
The present invention relates to methods of diagnosing susceptibility to Crohn's Diseaese by determining the presence or absence of susceptibility variants at the IL17RD locus. in one embodiment, the present invention provides a method of diagnosing and/or predicting susceptibility to Crohn's Disease by determining the presence or absence of an interaction between IL17RD Block 2 Haplotype 2 and IL23R Block 2 Haplotype 2 and/or IL12RB2 Haplotype 4, where the presence of an interaction between IL17RD Block 2 Haplotype 2 and IL23R Block 2 Haplotype 2 and/or IL12RB2 Haplotype 4 is indicative of susceptibility to Crohn's Disease.
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