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Method of producing tibolone metabolites by fermentation with Cunninghamella elegans

机译：秀丽隐杆线虫发酵生产替勃龙代谢物的方法

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摘要

A method of producing Δ^1,4-Tibolone (C₂₁H₂₆O₂), 10β-Hydroxy-Δ⁴-tibolone (C₂₁H₂₈O₃). 11α,15β-Dihydroxytibolone (C₂₁H₂₈O₄) and 11α,15β-Dihydroxy-Δ⁵-tibolone (C₂₁H₂₈O₄) by contacting tibolone and 3β,6β-Dihydroxytibolone (C₂₁H₃₂O₃) by contacting 3β-hydroxytibolone with Cunninghamella elegans (ATCC 10028b) is reported.

机译：一种制备Δ^{1,4 -替勃龙（C _{21 H _{26 O _{2 ），10β-羟基的方法-Δ^{4 -替勃龙（C _{21 H _{28 O _{3 ）。 11α，15β-二羟基替勃龙（C _{21 H _{28 O _{4 ）和11α，15β-二羟基-Δ^{5 -替勃龙（C _{21 H _{28 O _{4 ）通过替勃龙和3β，6β-二羟基替勃龙（C _{21 据报道，通过使3β-羟基替勃龙与秀丽线虫（ATCC 10028b）接触，可以得到H _{32 O _{3 ）。}}}}}}}}}}}}}}}}}}

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公开/公告号US2011124044A1

专利类型
公开/公告日2011-05-26

原文格式PDF
申请/专利权人 ATTAUR RAHMAN;MOHAMMED IQBAL CHOUDHARY;SYED ADNAN ALI SHAH;SHAMSUN NAHAR KHAN;
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申请/专利号US201113015553
发明设计人 ATTAUR RAHMAN;MOHAMMED IQBAL CHOUDHARY;SYED ADNAN ALI SHAH;SHAMSUN NAHAR KHAN;
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申请日2011-01-27
分类号C12P33/06;C12P33;C12P33/10;
国家 US
入库时间 2022-08-21 18:14:44

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