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Megaribavirin alone or combination of other antiviral, antioxidant and a perflubron emulsion for treatment of viral disease
Megaribavirin alone or combination of other antiviral, antioxidant and a perflubron emulsion for treatment of viral disease
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机译:单独使用巨核病毒唑或其他抗病毒药,抗氧化剂和全氟布仑乳剂的组合,用于治疗病毒性疾病
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摘要
The present invention is a novel method using a MegaRibavirin aerosol or a MegaRibavirin combination of therapeutics for the treatment of viral disease particularly the pandemic influenza strains “swine” 2009 H1N1 and H5N1. This invention utilizes Ribavirin in an aerosol Mega Dose (61-161 mg/ml) alone or combined with or without other antivirals, a perfluorocarbon emulsion and anti-inflammatory/anti-oxidants. Where applicable, the perfluorocarbon emulsion may dissolve these agents enabling a depot effect and possible protracted delivery. In addition perfluorocarbon emulsions have the possible added benefit of oxygen carrying capacity and alveolar nitric oxide sequestration, which may reduce peroxynitrite formation and decrease Influenza severity.
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