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HYPERBRANCHED POLYESTER AND A METHOD OF SYNTHESIZING A HYPERBRANCHED POLYESTER
HYPERBRANCHED POLYESTER AND A METHOD OF SYNTHESIZING A HYPERBRANCHED POLYESTER
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机译:超支化聚酯和合成超支化聚酯的方法
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摘要
The various embodiments herein provide a hyper branched polyester and a method of synthesizing the same. The embodiments herein also provide a method of encapsulating a drug into the void spaces of the polymer to act as a drug delivery system. The hyper branched polyester mer comprises an acidic moiety and an alcoholic moiety. The acidic moiety is citric acid monohydrate. The alcoholic moiety is glycerol. The acidic moiety and the alcoholic moiety are randomly arranged in the hyperbranched polymer. The method comprises of heating the mixture of citric acid and glycerol at temperatures of 90 to 150° C. by constant stirring for different time periods. In the method of encapsulation, the drug solution is drop-wise added to polymer solution at 37° C. by constant stirring for 24 h.
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