Isolated Antibody that specifically binds to and induces the degradation of receptor - 3 of Human Fibroblast Growth Factor (fgfr-3), Fragment of fgfr-3 Link Human Same, Pharmaceutical Composition and resulting product

摘要

Isolated Antibody that specifically binds with the receptor - 3 of Human Fibroblast Growth Factor (fgfr-3) (b) and 3 (FGFR III c) or Mutant forms of fgfr-3 and induces the degradation of the receptor.Cdrh1 comprises a sequence that has gymftsygis (SEC ID no: 1), which has a cdrh2 sequence wvstyngdtnyaqkfqg (SEC ID: 2 NS), which has a cdrh3 sequence vlgyydsidgyyygmdv (SEC ID no: 3), is a cdrl1 sequence ggnnigdksvh (SEC ID no: 4), a cdrl2 that the sequence LDT ERPs (sec. Id: 5 NS), and has a cdrl3 sequence qvwdsgsdhvv (SEC ID no: 6).Link Fragment of Human that fgfr-3 Antibody. Pharmaceutical composition containing same. Product containing Said monoclonal antibody or Fragment. Its use as a Medicine to treat cancer.