bicyclic aromatic compounds useful as inhibitors of mitogen-activated protein kinase-2 activated kinase-2, without as a use, process for the preparation and pharmaceutical composition and combination comprising said compounds

摘要

BICYCLIC AROMATIC COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASE-2 ACTIVATED BY PROTEIN KINASE ACTIVATED WITH MITOGEN, WITHOUT USE, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION UNDERSTANDING THE COMPOUND COMPOSED. Compound of formula (1) or a pharmaceutically acceptable salt or prodrug of the ester thereof: wherein the groups R1-R6, A and Y are as defined in the specification, as inhibitors of (MAPKAP or MK2 kinase-2).