methods for producing prasugrel hydrochloride, for producing free prasugrel with a reduced content of oxtp, and for producing a prasugrel acid addition salt, prasugrel hydrochloride, pharmaceutical composition, use of a pharmaceutical composition, free prasugrel, and, salt salt addition of prasugrel acid

摘要

METHODS TO PRODUCE PRASUGREL HYDROCHLORIDE, TO PRODUCE FREE PRASUGREL WITH A REDUCED OXTP CONTENT, AND TO PRODUCE A PRASUGREL ACID ADDITION SALT, PRASUGREL COMPOSITION, PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL COMPOSITION PRASUGREL ACID ADDITION The present invention is directed to the supply of prasugrel hydrochloride or the like with reduced OXTP content. A method for producing prasugrel hydrochloride with a low OXTP content comprising dissolving free prasugrel containing OXTP in an inert solvent and optionally adding hydrochloric acid to the reaction solution is also provided.