首页> 外国专利> n-protein fusion proteins of interest, nucleic acid, expression vector, host cell, protein production processes, process of preparing an n-protein protein / p protein complex of interest, pharmaceutical composition, use of a n protein of a paramixoviridae family virus, conjugate, diagnostic reagent, use of a fusion protein and detection method

n-protein fusion proteins of interest, nucleic acid, expression vector, host cell, protein production processes, process of preparing an n-protein protein / p protein complex of interest, pharmaceutical composition, use of a n protein of a paramixoviridae family virus, conjugate, diagnostic reagent, use of a fusion protein and detection method

机译:感兴趣的n蛋白融合蛋白,核酸,表达载体,宿主细胞,蛋白生产过程,制备感兴趣的n蛋白蛋白质/ p蛋白复合物的过程,药物组合物,副混合病毒科病毒的蛋白用途,缀合物,诊断试剂,融合蛋白的用途和检测方法

摘要

N-PROTEIN FUSION PROTEINS OF INTEREST, NUCLEIC ACID, EXPRESSION VECTOR, HOSTED CELL, PROTEIN PRODUCTION PROCESSES, PROCESS OF PREPARING A PROTEIN COMPONENT, NUT PROTEIN USE OF A VIRUS FROM THE PARAMIXOVIRIDAE FAMILY, CONJUGATE, DIAGNOSTIC REAGENT, USE OF A FUSION PROTEIN AND DETECTION METHOD. The present invention relates to N-protein fusion proteins of interest, possibly in the form of soluble complexes of N-protein of interest / P protein, with N and P proteins being proteins of a virus of the Paramixoviridae. When the protein of interest is an antigen, the present invention also addresses the vaccine compositions and diagnostic reagents that comprise these N-antigen fusion proteins or these N-antigen / protein P protein complexes. The N-protein fusion protein of interest it can also be used as a ½ vector to transport, in cells, molecules of therapeutic interest such as antiviral or anti-cancer molecules.
机译:兴趣的N蛋白融合蛋白,核酸,表达载体,细胞托管,蛋白生产过程,制备蛋白组分的过程,使用RAM虫科病毒的坚果蛋白,接合蛋白,诊断性念珠菌检测方法。本发明涉及目的N蛋白融合蛋白,可能是目的N蛋白/ P蛋白的可溶性复合物的形式,其中N和P蛋白是副混合病毒科病毒的蛋白。当目的蛋白质是抗原时,本发明还涉及包含这些N抗原融合蛋白或这些N抗原/蛋白质P蛋白复合物的疫苗组合物和诊断试剂。感兴趣的N蛋白融合蛋白也可以用作½载体,以在细胞中转运治疗感兴趣的分子,例如抗病毒或抗癌分子。

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