USE OF ALOE-EMODIN IN THE TREATMENT OF NEUROECTODERMAL TUMORS

摘要

The invention relates to the use as anti-cancer drug of a natural compound ofvegetal origin, known as aloe-emodin (AE). Indeed, said compound has proved tohave a specific biological activity of inhibition on the growth ofneuroectodermal tumors, without evident toxic effects. The compound accordingto the present invention has also proved to be cell-specific and ti does notshow any inhibition on the growth of other cell types such as for instancefibroblasts. This pharmacological profile, i.e. tumor-targeting and absence oftoxicity, makes said compound particularly advantageous in the treatment ofneuroectodermal tumors. Pharmaceutical compositions containing saidpharmacological agent can therefore be usefully used in the treatment of theforesaid pathologies.