HUMAN-PLACENTA-LIKE COMPOSITION CONTAINING A HUMAN-PLACENTA-DERIVED GROWTH FACTOR AND CYTOKINES, AND COSMETIC USE THEREOF

摘要

The present invention relates to a cosmetic composition restructured from a human-placenta-derived growth factor and cytokines. The present invention provides a cosmetic composition comprising, as active ingredients, 300 to 300,000 pg/ml of basic fibroblast growth factor-2 (FGF-2), 100 to 100,000 pg/ml of platelet-derived growth factor-AA (PDGF-AA), and 400 to 400,000 pg/ml of vascular endothelial growth factor (VEGF), and further comprising 40 to 40,000 pg/ml of Flt-3 Ligand, 300 to 300,000 pg/ml of RANTES (CCL5), 80 to 80,000 pg/ml of Interleukin-10 (IL-10), 80 to 80,0000 pg/ml of interferon-gamma-inducible protein-10 (IP-10), and 30 to 30,000 pg/ml of platelet-derived growth factor-BB (PDGF-BB), if needed. The present invention provides a cosmetic composition which exhibits excellent effects in wrinkle removal and skin-whitening even when applied in a small amount, as opposed to conventional cosmetic compositions containing placenta extracts in which unnecessary components are included.