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USE OF STAMP RELATED MOLECULES IN THE DIAGNOSIS AND INHIBITION OF OVARIAN CANCER CELLS

机译:邮票相关分子在卵巢癌细胞的诊断和抑制中的应用

摘要

The subject invention comprises methods for diagnosing ovarian cancer using a STAMP expression product biomarker, kits for diagnosing ovarian cancer using assays for the STAMP expression producing biomarker, compositions comprising STAMP siRNA, methods for inhibiting growth of ovarian cells expressing STAMP expression product, and methods for treating patients diagnosed with ovarian cancer. The invention is premised on the unexpected discovery that STAMP affects the physiologically relevant activity of ovarian cancer cell growth apparently independent of several steroid hormones.
机译:本发明包括使用STAMP表达产物生物标记物诊断卵巢癌的方法,使用用于产生STAMP表达的生物标记物的测定法诊断卵巢癌的试剂盒,包含STAMP siRNA的组合物,用于抑制表达STAMP表达产物的卵巢细胞生长的方法以及用于治疗被诊断患有卵巢癌的患者。本发明的前提是出乎意料的发现,即STAMP影响卵巢癌细胞生长的生理学相关活性,显然与几种类固醇激素无关。

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