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TEMPORALLY PATTERNED OVEREXPRESSION OF Foxg1 AND Emx2 TRANSCRIPTION FACTOR GENES IN NEURAL PRECURSORS FOR BRAIN TISSUE REPAIR
TEMPORALLY PATTERNED OVEREXPRESSION OF Foxg1 AND Emx2 TRANSCRIPTION FACTOR GENES IN NEURAL PRECURSORS FOR BRAIN TISSUE REPAIR
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机译:脑组织修复中神经前体中Foxg1和Emx2转录因子基因的时间型过表达
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摘要
The present invention relates to a recombinant expression vector suitable for gene therapy and able to effectively express in a differentially state specific manner Emx2 and/or Foxg polypeptides or functional fragments thereof in neural stem cells (NSCs) and/or in neuron- restricted progenitors (NPs)as well as a neural stem cell (NSCs), or a neuron-restricted progenitor (NPs) cell or a mixed cell population thereof transformed with such10 recombinant expression vector.
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