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Device for carrying out tests, in particular molecular biological tests

机译:用于进行检验,特别是分子生物学检验的装置

摘要

The device for performing molecular biological tests, comprises an object carrier on which molecular biological reference patterns are locally arranged in an area by a width and a length, where the reference patterns are potentially suitable in order to cooperate with counter reference present in a solution. The solution is guided for accelerating a reaction between the reference patterns and the counter reference by a pumping device (17) constant over the area. The object carrier is a part of a reaction chamber (11) with an inlet area (12) spaced apart for area, and an outlet area (13). The device for performing molecular biological tests, comprises an object carrier on which molecular biological reference patterns are locally arranged in an area by a width and a length, where the reference patterns are potentially suitable in order to cooperate with counter reference present in a solution. The solution is guided for accelerating a reaction between the reference patterns and the counter reference by a pumping device (17) constant over the area. The object carrier is a part of a reaction chamber (11) with an inlet area (12) spaced apart for area, and an outlet area (13) spaced apart for area. The solution of the reaction chamber flows from direction of the inlet area towards the direction of the outlet area. A flow element (38) is arranged between the inlet area of the reaction chamber and the area with the reference patterns, where the flow element deflects the solution flowing over the inlet area into the area of the reaction chamber in such a way that the flow cross-section of the solution is increased so that the solution flows in comparison with the same reaction chamber without the flow element over a width of the area observed transverse to the flow direction of the solution. The flow element has a height, which corresponds to the height of the reference patterns on the object carrier. The object carrier is overlaid from a covering element, which is a part of the reaction chamber. The flow element is arranged at the covering element on the side turned to the object carrier. The flow element extends itself over the total height of the reaction chamber between the object carrier and the covering element and is formed as a separate component. The flow element is formed on the object carrier or the covering element in a single piece manner. The flow element is formed through structuring the surface of the object carrier or the covering element and is arranged near to the inlet areas. The inlet area of the reaction chamber is widely formed in funnel-shaped manner such that the flow element is directly connected on the funnel-shaped extension in the flow direction of the solution. The flow element is aligned with the extension so that the flow element has a greater extension transverse to the flow direction than extension in the area of the beginning of the extension. The flow element has a round cross-section area, and is formed in cylindrical manner. The object carrier has a rectangular shape in the region of the area, and the area has a rectangular base surface. The width and length lie half of the width of the object carrier in the region of the area. The object carrier is formed in equal distance to the lateral edges. The distance between the flow element and the area on the one side and the flow element and the inlet area on the other side is equally large.
机译:用于执行分子生物学测试的装置包括目标载体,在该目标载体上分子生物学参考图案通过宽度和长度局部地布置在一个区域中,其中参考图案潜在地适合于与溶液中存在的反参考物配合。通过在该区域上恒定的泵送装置(17)引导溶液以加速参考图案和反参考之间的反应。物体载体是反应腔室(11)的一部分,反应腔室(11)的入口区域(12)按面积间隔开,出口区域(13)。用于执行分子生物学测试的装置包括目标载体,在该目标载体上分子生物学参考图案通过宽度和长度局部地布置在一个区域中,其中参考图案潜在地适合于与溶液中存在的反参考物配合。通过在该区域上恒定的泵送装置(17)引导溶液以加速参考图案和反参考之间的反应。物体载体是反应腔室(11)的一部分,其入口区域(12)间隔一定的面积​​,而出口区域(13)间隔一定的面积​​。反应室的溶液从入口区域的方向流向出口区域的方向。流动元件(38)布置在反应室的入口区域和具有参考图案的区域之间,其中,流动元件将流过入口区域的溶液偏转到反应室的区域中,使得流动溶液的横截面增加,使得与没有流动元件的相同反应室相比,溶液在横向于溶液流动方向的区域的整个宽度上流动。流动元件具有与对象载体上的参考图案的高度相对应的高度。物体载体由覆盖元件覆盖,该覆盖元件是反应室的一部分。流动元件在转向对象载体的一侧布置在覆盖元件上。流动元件在对象载体和覆盖元件之间的反应室的总高度上延伸,并形成为单独的组件。流动元件以单件形式形成在对象载体或覆盖元件上。流动元件通过构造物体载体或覆盖元件的表面而形成,并布置在入口区域附近。反应室的入口区域以漏斗形的方式广泛地形成,使得流动元件在溶液的流动方向上直接连接在漏斗形的延伸部上。流动元件与延伸部对准,使得流动元件横向于流动方向具有比延伸部的开始区域中的延伸部更大的延伸部。流动元件具有圆形的横截面,并且以圆柱形的方式形成。物体载体在该区域的区域中具有矩形形状,并且该区域具有矩形的底表面。宽度和长度在该区域的区域中是对象载体宽度的一半。物体载体以与侧边缘相等的距离形成。流动元件与一侧上的区域之间以及流动元件与另一侧上的入口区域之间的距离相等。

著录项

  • 公开/公告号EP2322276A1

    专利类型

  • 公开/公告日2011-05-18

    原文格式PDF

  • 申请/专利权人 ROBERT BOSCH GMBH;

    申请/专利号EP20100185269

  • 发明设计人 RUPP JOCHEN;

    申请日2010-10-01

  • 分类号B01L3/00;G01N33/543;

  • 国家 EP

  • 入库时间 2022-08-21 17:54:23

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