CASP POLYMORPHISM AS A PROGNOSTIC MARKER FOR LUNG CANCER AND METHOD FOR PREDICTING THE SURVIVALS AND THE RISK OF DEVELOPING LUNG CANCER USING THEM

摘要

PURPOSE: A marker for predicting risk and prognosis of lung cancer using SNP of CASP7 and/or CASP9 gene is provided to predict lung cancer occurrence possibility and to enhance survival rate of a patient with lung cancer. CONSTITUTION: A marker for predicting risk and prognosis of lung cancer contains comprises: a polynucleotide with 10 or more DNA sequences having 1151th base which is C or G in CASP7 gene of sequence number 1; a polynucleotide with 10 or more DNA sequences having 637th base which is C or T in CASP9 gene of sequence number 2; or complementary polynucleotide thereof. A composition for predicting risk and prognosis of lung cancer contains an agent which is able to measure mRNA or protein level of CASP7 or CASP9 gene.