GENE IMPLICATED IN OSTEOARTHRITIS AND USE THEREOF

摘要

PURPOSE: A composition for preventing or treating arthritis using Barx 1(BarH-like homeobox 1) molecule is provided to improve viability of chondrocytes. CONSTITUTION: A composition for preventing or treating arthritis contains a nucleic acid molecule which suppresses expression of a nucleotide sequence encoding an amino acid sequence of sequence number 2. The nucleotide sequence has nucleotide sequence of sequence number 1. The nucleic acid molecule is shRNA, siRNA, miRNA, ribozyme, PNA(peptide nucleic acids), or antisense oligonucleotide.