METHOD OF CHANGES lipid peroxidation products (conjugated diene, hydroperoxides, malondialdehyde) in the investigated tissue caused by simultaneous or selective excitation PERIPHERAL M, N-cholinergic STRUCTURES cell plasma membrane of endogenous ATSETINHOLINOM USING antiholinesteraznae MECHANISMS IN THE COLD LOAD (in the experiment)

摘要

FIELD: medicine.;SUBSTANCE: for content change of lipid peroxidation products in laboratory rats caused by simultaneous or selective excitation of peripheral muscarine-sensitive and nicotine-sensitive structures (M- and N-cholinoceptive structures) of a plasmatic cell membrane, anticholinesterase accumulation mechanisms of endogenous acetylcholine in tissues are used. 30 minutes prior to the introduction of proserin, the rats are prescribed with: benzohexonium for activation of M-cholinoceptive structures only; methacin and atropine for activation of N-cholinoceptive structures only; proserin only is required for simultaneous excitation of peripheric M- and N-cholinoceptive structures. The experimental animals are placed in an environmental camera for cooling.;EFFECT: method allows changing the content of lipid peroxidation products in laboratory rats caused by simultaneous or selective excitation of peripheral M- and N-cholinoceptive structures of the plasmatic cell membrane with using anticholinesterase accumulation mechanisms of endogenous acetylcholine in tissues in the cold-loaded environment.;4 tbl