APPLICATION OF His-Ser-Leu-Gly-Lys-Trp-Leu-His-Pro-Asp-Lys-Phe PEPIDID INDIVIDUALLY OR IN COMBINATION WITH A Gly-Arg-Gly-Asp-Asn-Pro-OH PEPTIDE AS A THERAPEUTIC

摘要

1. The combination of His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe and Gly-Arg-Gly-Asp-Asn-Pro-OH peptides or their salts or hydrates. ! 4. The combination according to claim 2, where the peptides are contained in combination in an amount of from 30% by weight to 70% by weight to 70% by weight to 30% by weight. ! 3. The combination according to claim 1 for use in a medicinal product. ! 4. The use of the peptide His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe or a combination according to claim 1, 2, or 3 for the preparation of a pharmaceutical composition for treatment and / or prevention malignant tumors, autoimmune diseases, fibrosis, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and blood vessel diseases and metabolic diseases. ! 5. The use according to claim 4, where the malignant tumor, autoimmune disease, fibrosis, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and vascular disease or metabolic disease selected infections Streptococus pneumoniae associated with infection Streptococus pneumoniae diseases, and namely hemolytic uremic syndrome, pneumonia, meningitis, complications of cystic fibrosis, middle ear diseases, infections in the bloodstream, sinus and ear infections, acute sinusitis, otitis media, ost eomyelitis, septic arthritis, endocarditis, peritonitis, pericarditis and brain abscess. ! 6. The use of the peptide His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe or a combination according to claim 1 or 2, or 3 for the preparation of an oral composition for infants, toddlers age and / or preschool children. ! 7. The use of the peptide His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe or a combination according to claim 1 or 2, or 3 to obtain a lyophilized coc