APPLICATION OF THE FIBRINOGEN RECEPTOR ANTAGONIST AND / OR FOLICULAR GONADOLIBERIN PEPTIDE AS A THERAPEUTIC AGAINST TREATMENT OF STREPTOCOCCUS PNEUMONIAE INFECTION

摘要

1. The combination of peptides Ac-Pen-Arg-Gly-Asp-Cys-OH and Thr-Asp-Thr-Ser-His-His-Asp-Gln-Asp-His-Pro-Thr-Phe-Asn-OH or their salts hydrates or deacetylated forms. ! 2. The combination according to claim 1, where the peptides are contained in combination in an amount of from 30 wt.% To 70 wt.% To 70 wt.% To 30 wt.%. ! 3. The combination according to claim 1 for use in medicine. !four. The use of the Ac-Pen-Arg-Gly-Asp-Cys-OH peptide or a combination according to claim 1, 2, or 3 for the preparation of a pharmaceutical composition for the treatment and / or prevention of a malignant tumor, autoimmune diseases, fibrosis, inflammatory diseases, neurodegenerative diseases , infectious diseases, lung diseases, heart and blood vessel diseases and metabolic diseases. ! 5. The use of the peptide according to claim 4, where the malignant tumor, autoimmune disease, fibrosis, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and vascular disease or metabolic disease selected infections Streptococus pneumoniae associated with infection Streptococus pneumoniae diseases, namely, hemolytic uremic syndrome, pneumonia, meningitis, complications of cystic fibrosis, middle ear diseases, infections in the bloodstream, sinus and ear infections, acute sinusitis, otitis media ear, osteomyelitis, septic arthritis, endocarditis, peritonitis, pericarditis and brain abscess. ! 6. The use of the peptide Ac-Pen-Arg-Gly-Asp-Cys-OH to obtain a composition for oral administration to newborns, toddlers and / or preschool children. ! 7. The use of the peptide Ac-Pen-Arg-Gly-Asp-Cys-OH to obtain a lyophilized composition or a buffer liquid composition. ! 8. A pharmaceutical composition comprising a combination according to claim 1 for less